International Workshop on Very High Energy Electron Radiotherapy (VHEE’25)
STFC, Daresbury Laboratory

The 4th workshop on Very High Energy Electron Radiotherapy (VHEE-RT) will take place on 15th - 17th September 2025 at the Cockcroft Institute, Daresbury, U.K.
Its objective is to bring together researchers studying VHEE-RT. The workshop will serve as a forum for scientists and engineers from around the world to review the latest developments in the field, to exchange ideas and discuss cutting-edge topics. The workshop will consist of plenary sessions, industry session, student posters and associated poster prizes.
The latest biological, medical physics and machine development aspects will be discussed by experts in the field, and the way forward will be charted. In particular, the steps needed to needed to facilite a VHEE-RT-capable clinical machine will be focussed on. The major achievements in the field, together with the important future challenges will be highlighted.
This workshop is endorsed by ICFA (International Committee for Future Accelerators).
PhD students are invited to submit abstracts to VHEE25@stfc.ac.uk which will be presented during a dedicated poster session. Best posters will also have the possibility to represent their work in a short oral presentation. Financial support for local expenses will be offered to a few students. A written application for a bursary should be sent via e-mail by 29th June to the VHEE25@stfc.ac.uk together with a description of the related work, an abstract of the contribution to the workshop and two supporting letters.
Please let us know in case you need an invitation letter.
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08:00
Coach pickup from hotels: Park Royal@ Premier Inn@ Village Hotel@
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08:30
Registration
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1
WelcomeSpeakers: Jim Clarke (STFC Daresbury Laboratory), Stewart Boogert (-)
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Setting up the scene for VHEEConvener: Deepa Angal-Kalinin (STFC)
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2
Introduction and progress towards technology readinessSpeaker: Roger Jones (Univ. Manchester/Cockcroft Inst.)
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Medical physics aspectsSpeaker: Emil Schueler (UT MD Anderson Cancer Center)
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5
Investigating the biological effects of beam parameters to guide technological developments for clinical applications.Speaker: Marie-Catherine Vozenin (HUG/UNIGE)
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2
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10:50
Coffee Break
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Setting up the scene for VHEEConvener: Deepa Angal-Kalinin (STFC)
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6
VHEE program at Curie including the clinical perspectivesSpeaker: Gilles Créhange (Institute Curie)
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DiscussionSpeaker: Deepa Angal-Kalinin (STFC)
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6
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Facility Updates Session
Chair: Angeles Faus-Golfe
Convener: Angeles Faus-Golfe (IJCLab)- 8
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13:00
Lunch Break & Group Photo
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Facility Updates Session
Chair: Angeles Faus-Golfe
Convener: Angeles Faus-Golfe (IJCLab)- 11
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12
The new beamline and biolab at FLASHlab@PITZSpeaker: Xiangkun Li (DESY)
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13
Status of HyperVIEW @ Irvine, CaliforniaSpeaker: Christopher Barty
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14
Ultracompact accelerator for electron Intrabeam RTSpeaker: Matthias Fuchs
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15
DiscussionSpeaker: Angeles Faus-Golfe
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CLARA Tours & Student Poster Session
Chair: Student poster Session - Roger Jones
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18:15
Coach pickup for transfer to hotels
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08:00
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08:15
Coach pickup from hotels: Park Royal@ Premier Inn@ Village Hotel@
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Biological and Medical PhysicsConvener: Marie-Catherine Vozenin
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16
Experimental conditions for the FLASH effect: Systematic in vivo studiesSpeaker: Anouk Sesink (CHUV)
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17
Very High Energy Electrons: Clinical Perspective and ConstraintsSpeaker: Jake Pensavalle (Sordina IORT Technologies S.p.A.)
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18
The challenge of VHEE planning: providing robust plans that will ease a FLASH deliverySpeaker: Alessio Sarti (Sapienza Rome University)
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19
Beam modelling, dose calculation and potential clinical application of a scanned electron beam with ultra-high dose rateSpeaker: James Bedford (The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust)
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20
The Dose per Bunch Controls Morphological Outcome in Zebrafish Embryos exposed to VHEE BeamsSpeaker: Louis Kunz (UNIGE)
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21
DiscussionSpeaker: Marie-Catherine Vozenin (HUG/UNIGE)
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16
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11:00
Coffee Break
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VHEE non conventional (Laser Plasma)Convener: Alessandro Flacco
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22
Perspectives for VHEE with laser plasma acceleration technologySpeaker: Timo Eichner
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23
The I-LUCE laser-based acceleration facility at INFN and its perspectives for electron acceleration in FLASH and VHEE applicationsSpeaker: Roberto Catalano (INFN Catania)
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24
Status of electron acceleration and perspectives for VHEE with laser-plasma acceleration at ELI-BeamlinesSpeaker: Carlo Lazzarini (ELI ERIC ELI Beamlines Facility)
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25
Recent progress on laser-driven Very High Energy Electron radiotherapySpeaker: Zhiyuan Guo (Tsinghua University)
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Application of laser-driven high energy electrons to radiation biology and medical physics at LOASpeaker: Alessandro Flacco
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22
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13:00
Lunch
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VHEE non conventional (Laser Plasma)
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27
Progress towards 100 Hz operation of the VHEE beamline at ILILSpeaker: Gabriele Bandini (INO, CNR)
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28
DiscussionSpeaker: Alessandro Flacco (LOA)
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27
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Dosimetry and DetectorsConvener: Anna Subiel
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29
Dosimetry codes of practice: are they applicable to VHEE RT?Speaker: Hugo Palmans (NPL)
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30
Dosimetry at ultra high dose rates at PITZ and ARESSpeaker: Oliver Stein (DESY)
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31
Diamond detectors for UHDR-VHEE dosimetrySpeaker: Gianluca Verona Rinati (Uni of Rome Tor Vergata)
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Dose increment via coherent stopping of VHEE in ultraintense irradiationsSpeaker: alessandro Curcio (UniRoma)
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15:40
Coffee Break
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Dosimetry and DetectorsConvener: Anna Subiel
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33
Beam Position Monitoring of Electron Beams with the hybrid Pixelated Detector Dosepix and Nitrogen Fluorescence LightSpeaker: Florian Beißer (FAU Erlangen)
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34
UHDR-VHEE dosimetry with Silicon Carbide detectorsSpeaker: Giuliana Milluzzo (INFN- Catania Division)
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35
Novel approaches for UHDR-VHEE through ionization chambersSpeaker: Marco Montefiori (CPFR)
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36
DiscussionSpeaker: Anna Subiel (NPL)
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33
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17:30
Coach Pick Up for Workshop Dinner
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18:30
Workshop Dinner
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08:15
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07:45
Coach pickup from hotels: Park Royal@ Premier Inn@ Village Hotel@
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Industries for medical technologies
Chair: Luigi Palumbo
Convener: Luigi Palumbo (University of Roma)-
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Industry VHEE devices: THALESSpeakers: Elisabeth Dehe (THALES), Terence SCHUERMANS (THALES)
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Industry VHEE devices: THERYQ (FLASHDEEP)Speaker: Philippe Liger (THERYQ)
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Industry VHEE devices: Lumitron TechnologiesSpeaker: Christopher Barty (Lumitron Technologies & Univ. of California, Irvine)
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DiscussionSpeaker: Luigi Palumbo
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37
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10:15
Coffee Break
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Accelerators R&D and Technologies for Medical
Chair: Roberto Corsini
Convener: Roberto Corsini (CERN)- 42
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43
Experience of building an X-band compact 300MeV linac (TBC)Speaker: Li Hongyu (Tsinghua University)
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DiscussionSpeaker: Roberto Corsini (CERN)
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Student PresentationsConveners: Lucia Giuliano, Prof. Manjit Dosanjh
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Power and Beam Dynamics Optimization for a VHEE FLASH LINACSpeaker: Stefano Farina (La Sapienza University)
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47
Predictive Modelling of Radiotherapy LINAC Downtime using Variational Autoencoders.Speaker: Samuel Leadley (University of Oxford)
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48
The optimal Very High Energy Electron beam parameters to treat glioblastoma using Pencil Beam ScanningSpeaker: Katie O’Shea (CHUV (Lausanne University Hospital))
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CLEAR, operational status and VHEE activities.Speaker: Giacomo Tangari (CERN / Sapienza University of Rome)
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50
Transfer Matrix Formalism of In-Air VHEE Beam Profile Measurements at PEERSpeaker: Joel Valerian (University of Melbourne)
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Development of Scattering Systems for Tumour Conformality with VHEE BeamsSpeaker: Sabrina Wang (Oxford University, JAI)
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52
Dosimetric Impact of Anatomical Change on VHEE and VMAT Plans: A Comparative Robustness StudySpeaker: Fabio D'Andrea (UMAN, CI)
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53
External Injection into Plasma to Produce VHEE BeamsSpeaker: Jordan Byrne (UMAN, CI)
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46
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13:30
Lunch
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07:45