Speaker
Description
The FMX (Frontier Microfocusing Macromolecular Crystallography) beamline at the NSLS-II light source has developed a new experimental station for fixed target time-resolved serial crystallography on biological systems. We present here the controls-system for a chip scanner which enables the rapid collection of large numbers of room temperature crystallographic measurements on biological samples. In addition to static measurements, samples can be excited in a pump-probe scheme by the injection of compounds suspended in liquid through a microdrop dispensing system, at timed intervals preceding the measurement. Enabling this has required the implementation of a full stack integrated solution, involving direct programming of the powerPMAC motion controller, control of motion, triggering and detectors through EPICS, data collection through Ophyd/Bluesky, and the implementation of an optional GUI for control of the experiment. Here, I will outline the components involved in this process, as well as the successes and pitfalls which we have encountered during the implementation and testing of the scanner.
