DULIA-BIO - Bio Sciences in Deep Underground Laboratories

Session

Studies of Life in Low Background Radiation

20 Aug 2024, 11:00

Council Chamber (The Guildhall, York)

Conveners

Studies of Life in Low Background Radiation

• Carlos Garay (Canfranc Underground Laboratory)

Studies of Life in Low Background Radiation

• Aldo Ianni (INFN LNGS)

Studies of Life in Low Background Radiation

• Paul Scovell (STFC Boulby Underground Laboratory)

13. The REPAIR project: investigating the effects of sub-natural background radiation exposure within SNOLAB - (in-person)

Chris Thome

20/08/2024, 11:00

20-minute talk + 10-minute questions

Living systems are continually exposed to background ionizing radiation and have evolved and adapted in its presence. However, the potential biological impacts of this chronic low dose rate exposure remain poorly understood. The REPAIR (Researching the Effects of the Presence and Absence of Ionizing Radiation) project, located at SNOLAB in Sudbury,...

14. Adaptive and evolutionary responses of microalgae to ultra-low radioactivity at the Modane Underground Laboratory - (in-person)

Vincent Breton

20/08/2024, 11:30

20-minute talk + 10-minute questions

Our knowledge is limited on the long-term impact of natural radioactivity on living organisms, particularly those inhabiting aquatic ecosystems. Living organisms have developed resistance to ionizing radiation, but it remains to be determined whether they have fully adapted to this radiation or whether they continue to be influenced by this stress....

15. Effects of microgravity and below-background radiation in the pathogenesis of Orsay virus infection of Caenorhabditis elegans - (remote)

Santiago Elena

20/08/2024, 12:00

20-minute talk + 10-minute questions

In the near future, space missions will be extended to meet exploration goals. Space conditions, particularly microgravity and radiation, present unique stresses for organisms that they have not evolved to handle. The impact of these conditions on viral infections and host antiviral defenses is not well understood. C. elegans, a model organism, and its...

19. Investigating the effect of low background radiation in the origin of animals - (remote)

Patricia Suárez Ara

20/08/2024, 16:00

20-minute talk + 10-minute questions

Background radiation is an abiotic component of Earth's surface environment that has potentially influenced biophysical and biochemical processes throughout evolution. One of the most critical evolutionary transitions was the emergence of multicellularity in animals, which led to the vast diversity observed in animals today. By studying the unicellular...

20. DISCOVER22 radiobiology project at Gran Sasso National Laboratory - (remote)

Patrizia Morciano

20/08/2024, 16:30

20-minute talk + 10-minute questions

Patrizia Morciano1,2; Matthias Laubenstein1; Valentina Dini3,4; Giorgio Baiocco5,6; Valeria Conte7; Antonella Sgura8,9 1INFN-Laboratori Nazionalli del Gran Sassso, Assegi L’Aquila, Italy 2Università degli Studi dell’Aquila, Dipartimento di Medicina clinica, sanità pubblica, scienze della vita e dell'ambiente, L’Aquila, Italy 3 Centro Nazionale di...

21. Microdosimetry of low dose radiation fields in the framework of the DISCOVER22 project - (remote)

Anna Bianchi

20/08/2024, 17:00

20-minute talk + 10-minute questions

While high doses of ionizing radiation are known to harm human health, the effects of low dose radiation (LDR) are debated. LDR has been shown to influence immune responses, possibly inducing beneficial effects, but the underlying mechanisms are not well understood. Research on LDR effects is often affected by uncertainties like unmonitored radiation...

33. DULIA-BIO Dinner

20/08/2024, 17:30

Information slide for tonights dinner

22. The Effect of Natural Background Radiation on Stem Cell Biology - (in-person)

Umberto Galderisi

21/08/2024, 09:00

20-minute talk + 10-minute questions

A number of experiments have shown that cells grown under chronic and/or acute low doses of radiation exhibit growth and fitness traits different from cells grown at control radiation levels, suggesting a radioadaptive response. Adult stem cells are a rare population of undifferentiated cells located within a differentiated organ or tissue, in a...

23. Stem cells long term preservation - (remote)

Guillaume Warot

21/08/2024, 09:30

20-minute talk + 10-minute questions

24. Does ionizing radiation affect HIV release from human macrophages? - (remote)

David Nkwe

21/08/2024, 10:00

20-minute talk + 10-minute questions

Viruses have small genomes that encode a few proteins required for their propagation. To complete their replication cycles, viruses usurp host cell machineries. By studying virus replication, we gain insights into the biology of host cells and organisms. A classic example is the human immunodeficiency virus (HIV), the most studied virus. HIV affects host...