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DULIA-BIO - Bio Sciences in Deep Underground Laboratories

19–22 Aug 2024
The Guildhall, York
Europe/London timezone

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Contribution List

33 / 33
4. Welcome and Context - (in-person)
Sean Paling (STFC)
19/08/2024, 13:30
5. Underground Laboratories: A Brief Review - (in-person)
Aldo Ianni
19/08/2024, 14:00

20-minute talk + 10-minute questions
6. Biology, astrobiology and planetary exploration studies at Boulby Underground Lab - (in-person)
Charles Cockell
19/08/2024, 14:30

20-minute talk + 10-minute questions

Since 2013, the Boulby Underground Laboratory has been used as a subsurface scientific site to study life in deep subsurface environments and to test equipment for the robotic and human exploration and settlement of space. Over ten subsurface campaigns as part of MINAR (Mine Analogue Research) have been hosted by the laboratory. They have involved teams...
7. Overview of Life in low background radiation studies - (in-person)
Carlos Garay
19/08/2024, 15:30

20-minute talk + 10-minute questions
8. Beyond Earth Human Habitation Studies Underground - (in-person)
Alex Iordachescu
19/08/2024, 16:00

20-minute talk + 10-minute questions
9. Earth/Moon/Mars studies of Extreme Environments - (remote)
Bernard Foing
19/08/2024, 16:30

20-minute talk + 10-minute questions

EuroMoonMars is an ILEWG/LUNEX programme in collaboration with space agencies, academia, universities and research institutions and industries. The programme includes research activities for data analysis, instruments tests and development, field tests in MoonMars analogue, pilot projects , training and hands-on workshops , and outreach activities....
30. Bioscience at SURF - (remote)
Marcus Horn
19/08/2024, 17:00

20-minute talk + 10-minute questions

The Sanford Underground Research Facility (SURF) with its vast underground footprint provides opportunities for research activities beyond astroparticle physics, rare event searches and neutrino physics. SURF is hosting biology research focusing on microorganisms in extreme environments, biofilms, as wells as astrobiology and in-situ cultivation. A brief...
10. SNOLAB: Underground Facilities for Biological Experiments - (in-person)
Shaun Hall
20/08/2024, 09:00

20-minute talk + 10-minute questions

SNOLAB, with its underground facilities at 2070 m within Creighton Mine in Sudbury, Ontario, Canada, has already hosted biological experiments, including FlaME and REPAIR, providing a unique environment for experiments requiring isolation from surface background radiation. Improvements at SNOLAB, including the introduction of local ICP-MS analysis for...
11. Biosciences at Callio Lab - (in-person)
Jari Joutsenvaara
20/08/2024, 09:30

20-minute talk + 10-minute questions

Callio Lab is one of the northernmost deep underground laboratories and research environments in Europe. It is located at the Pyhäsalmi mine, Finland. The early focus of the laboratory has been underground physics, but since 2015, it has been open for trans- and multidisciplinary research and art. Pilot projects with underground farming, including plant...
12. Prospects of Bio Science Research in Deep Underground Laboratories in Africa: Botswana Perspective - (in-person)
Tebogo Kwape
20/08/2024, 10:00

20-minute talk + 10-minute questions

There is currently no Deep Underground Laboratory in Africa despite the research challenges Africa faces in Bio Science, some of these research challenges can be addressed partly through the existence and utilization of Deep Underground Laboratories. There is however one envisaged project to construct a Deep underground laboratory in South Africa, named...
13. The REPAIR project: investigating the effects of sub-natural background radiation exposure within SNOLAB - (in-person)
Chris Thome
20/08/2024, 11:00

20-minute talk + 10-minute questions

Living systems are continually exposed to background ionizing radiation and have evolved and adapted in its presence. However, the potential biological impacts of this chronic low dose rate exposure remain poorly understood. The REPAIR (Researching the Effects of the Presence and Absence of Ionizing Radiation) project, located at SNOLAB in Sudbury,...
14. Adaptive and evolutionary responses of microalgae to ultra-low radioactivity at the Modane Underground Laboratory - (in-person)
Vincent Breton
20/08/2024, 11:30

20-minute talk + 10-minute questions

Our knowledge is limited on the long-term impact of natural radioactivity on living organisms, particularly those inhabiting aquatic ecosystems. Living organisms have developed resistance to ionizing radiation, but it remains to be determined whether they have fully adapted to this radiation or whether they continue to be influenced by this stress....
15. Effects of microgravity and below-background radiation in the pathogenesis of Orsay virus infection of Caenorhabditis elegans - (remote)
Santiago Elena
20/08/2024, 12:00

20-minute talk + 10-minute questions

In the near future, space missions will be extended to meet exploration goals. Space conditions, particularly microgravity and radiation, present unique stresses for organisms that they have not evolved to handle. The impact of these conditions on viral infections and host antiviral defenses is not well understood. C. elegans, a model organism, and its...
16. Tracking ancient and modern microbial life in salt and brines of Boulby Mine (N Yorkshire) or: What to look out for on Mars - (in-person)
Jens Holtvoeth
20/08/2024, 13:30

20-minute talk + 10-minute questions

Our study aims to produce a biogeochemical fingerprint of fossil and living microbial organisms in salt and brines of the mine at Boulby by analysing lipid biomarkers (alkyl lipids, GDGTs) and DNA. Outcomes are expected to contribute insights into late Permian hydrology and paleoecology, extremophile ecology and astrobiology. Biomarker distributions in...
17. Astrobiology in Subsurface Extreme Environments: Utilizing Brines and Minerals for Planetary Exploration - (remote)
Scott Perl
20/08/2024, 14:00

20-minute talk + 10-minute questions

The understanding of microbial life in extreme (salty) environments regarding survivability, ecology, and nutrients on Earth can be applied to Martian subsurface regolith and salt mineral features precipitated meters to km below the crust. The MINAR program at the Boulby Underground Laboratory has given rise to significant insights to 250 Gyr evaporite...
18. Biophysical and microbiological research at the deep underground low radiation background laboratory (DULB-4900) and tunnel of Baksan Neutrino Observatory - (remote)
Mikhail Zarubin
20/08/2024, 14:30

20-minute talk + 10-minute questions

Deep underground laboratories at physical research centers possess an outstanding potential for hosting biological experiments in fields of biophysics, radiobiology, astrobiology, microbiology and medicine. Molecular genetics group of DLNP JINR initiated cooperative studies in the deep underground low radiation background laboratory (DULB-4900) and...
31. How statistical physics limits microbial life under extreme conditions: foraging and motility
Laurence Wilson
20/08/2024, 15:00

20-minute talk + 10-minute questions

The ability of cells to move - their motility - is important across a very wide range of species from eukaryotes, bacteria and archaea. Although their motility structures (such as cilia and flagella) evolved from different precursor organelles, the physical laws that constrain their performance are the same. Archaea in the deep subsurface environment...
19. Investigating the effect of low background radiation in the origin of animals - (remote)
Patricia Suárez Ara
20/08/2024, 16:00

20-minute talk + 10-minute questions

Background radiation is an abiotic component of Earth's surface environment that has potentially influenced biophysical and biochemical processes throughout evolution. One of the most critical evolutionary transitions was the emergence of multicellularity in animals, which led to the vast diversity observed in animals today. By studying the unicellular...
20. DISCOVER22 radiobiology project at Gran Sasso National Laboratory - (remote)
Patrizia Morciano
20/08/2024, 16:30

20-minute talk + 10-minute questions

Patrizia Morciano1,2; Matthias Laubenstein1; Valentina Dini3,4; Giorgio Baiocco5,6; Valeria Conte7; Antonella Sgura8,9 1INFN-Laboratori Nazionalli del Gran Sassso, Assegi L’Aquila, Italy 2Università degli Studi dell’Aquila, Dipartimento di Medicina clinica, sanità pubblica, scienze della vita e dell'ambiente, L’Aquila, Italy 3 Centro Nazionale di...
21. Microdosimetry of low dose radiation fields in the framework of the DISCOVER22 project - (remote)
Anna Bianchi
20/08/2024, 17:00

20-minute talk + 10-minute questions

While high doses of ionizing radiation are known to harm human health, the effects of low dose radiation (LDR) are debated. LDR has been shown to influence immune responses, possibly inducing beneficial effects, but the underlying mechanisms are not well understood. Research on LDR effects is often affected by uncertainties like unmonitored radiation...
33. DULIA-BIO Dinner
20/08/2024, 17:30

Information slide for tonights dinner
22. The Effect of Natural Background Radiation on Stem Cell Biology - (in-person)
Umberto Galderisi
21/08/2024, 09:00

20-minute talk + 10-minute questions

A number of experiments have shown that cells grown under chronic and/or acute low doses of radiation exhibit growth and fitness traits different from cells grown at control radiation levels, suggesting a radioadaptive response. Adult stem cells are a rare population of undifferentiated cells located within a differentiated organ or tissue, in a...
23. Stem cells long term preservation - (remote)
Guillaume Warot
21/08/2024, 09:30

20-minute talk + 10-minute questions
24. Does ionizing radiation affect HIV release from human macrophages? - (remote)
David Nkwe
21/08/2024, 10:00

20-minute talk + 10-minute questions

Viruses have small genomes that encode a few proteins required for their propagation. To complete their replication cycles, viruses usurp host cell machineries. By studying virus replication, we gain insights into the biology of host cells and organisms. A classic example is the human immunodeficiency virus (HIV), the most studied virus. HIV affects host...
25. Opportunities and challenges of deep underground science facilities and research laboratories: An extended review of current status - (remote)
Goabaone Gaobotse
21/08/2024, 11:00

20-minute talk + 10-minute questions

Deep underground science facilities and research laboratories have the potential to provide a sustainable outlet for the disposal of radioactive waste. These deep underground science facilities and research laboratories can also be used to train qualified personnel. Working underground affords a highly controlled and stable environment for research and...
26. Bioscience and Beyond Outreach at Boulby - (in-person)
Jonathan Gutteridge (STFC)
21/08/2024, 11:30

20-minute talk + 10-minute questions
27. DISCUSSION: Reproducibility for future underground bio-sciences - (in-person)
Carlos Garay, Charles Cockell
21/08/2024, 13:00
32. DISCUSSION: Future of bioscience research and the role of underground laboratories
ALL (Organising Committee)
21/08/2024, 13:45
28. DISCUSSION: Specifications and requirements for a future underground bio-sciences lab
Emma Meehan (STFC), Paul Scovell (STFC), Sean Paling (STFC)
21/08/2024, 14:45
3. 06:00-16:30 - Boulby Underground Laboratory Visit
22/08/2024, 06:00

Max. 20 people (email will be sent to all attendees who have requested visit)

Transport from York to Boulby Underground Laboratory

06:00 pick-up – York Train Station to Boulby Mine
PLEASE ARRIVE BY 05:50 OUTIDE THE FONT OF THE STATION
The transport is Coatham Coaches, Driver: Mark Sanderson +44 (0)7904 015644

14.30 pick-up – Boulby to York Train Station

Dear All,

We are very...
29. DISCUSSION: Future of bioscience research and the role of underground laboratories
ALL (Organising Committee)
2. DISCUSSION: Future strategies for Dulia-Bio
ALL (Org Committee)
1. Mine Analogue Research (MINAR). The Boulby Underground Laboratory as a Planetary and Astrobiology Scientific Site and Testbed
Charles Cockell
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